Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 45, listelenen: 1-20
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Activation of TRESK Channels Ameliorates Pain and Neurogenic Inflammation in a Nitroglycerin-Induced Migraine Model in Rats
(Wiley, 2023)We investigated effects of activation of TRESK channels by selective activator cloxyquin on excitotoxic-induced brain injury and neuroinflammation involving brain mast cells and inflammatory cytokines in neonatal rats. ... -
Alkaline Phosphatase is not Associated with Insulin Resistance: A Retrospective Cross-Sectional Study
(2020)Background: Many epidemiologic studies suggested that vitamin D deficiency is associated with obesity but the relationship between obesity and alkaline phosphatase (ALP) is controversial. In this study association ... -
Alpha-lipoic acid could be a promising treatment in steroid-induced osteonecrosis
(Verduci International, 2022)OBJECTIVE: Glucocorticoid-induced osteonecrosis is a serious debilitating health problem. In the present study, we investigated the effects of alpha-lipoic acid on glucocorticoid-induced osteonecrosis in rats. MATERIALS ... -
The Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and Prediabetes
(Mdpi, 2023)In this study, we aimed to reveal the pro-inflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabetes. We recruited 84 prediabetes ... -
Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms
(Aves, 2020)Background/Aims: Astaxanthin (ATX) is a naturally occurring carotenoid and a potent antioxidant. Various anti-inflammatory effects of ATX have been examined. We aimed to investigate the protective effect of ATX and its ... -
Can Acellular Dermal Matrix and Kombucha Cellulose Membrane Be Used in Calvarial Reconstruction?
(Galenos Publ House, 2023)Amaç: Amacımız aselüler dermal matriks (ADM) ve Kombucha membranının (KM) kalvarial dura onarımında uygulanabilirliğini araştırmaktı. malzeme kusurları. Yöntemler: Wistar sıçanları üzerinde yapılan bir çalışmada altı ... -
Can circulating oxidative stress-related biomarkers be used as an early prognostic marker for COVID-19?
(Frontiers Media Sa, 2023)Arka Plan Oksidatif stres birçok hastalığın patogenezinde önemli bir rol oynar. Bu çalışma, yeni COVİD-19 hastalarında nükleer faktör kappa B (NF-kappa B) ile oksidatif stres arasındaki ilişkiyi ve hastalığın ciddiyetini ... -
Circulating mir-132, mir-146a, mir-222, and mir-320 expression in differential diagnosis of women with polycystic ovary syndrome
(Acta Endocrinologica-Bucharest, 2022)Purpose. The aim of the study was to investigate whether the circulating miR-132, miR-146a, miR-222, and miR-320 levels are used in the differential diagnosis of women with polycystic ovary syndrome (PCOS) and ... -
The clinical significance of circulating mir-21, mir-142, mir-143, and mir-146a ın patients with prostate cancer
(Society of Medical Biochemists of Serbia, 2022)Background: Prostate cancer (PCa) is the most common type of solid tissue cancer among men in western countries. In this study, we determined the levels of circulating miR-21, miR-142, miR-143, miR-146a, and RNU 44 levels ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
(Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects
(Acta Cırúrgıca Brasıleıra, 2021)Purpose: To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of esophageal damage and stricture formation due to esophageal caustic burns in rat model comparing with prednisolone. Methods: Caustic ... -
Could Prior COVID-19 Affect the Neutralizing Antibody after the Third BNT162b2 Booster Dose: A Longitudinal Study
(MDPI, 2023)Aşılama, devam eden COVID-19 salgını sırasında hastalığın yayılmasını önlemek için temel bir halk sağlığı önlemidir. Konakçının geliştirdiği immün yanıt veya aşının oluşturduğu immünolojik yanıtın devam etmesi, salgının ... -
Effect of Tacrolimus on Peripheral Nerve Regeneration in Allograft Transplantation: A Light and Electron Microscopic Study
(Baskent Unıv, 2021)Objectives: Peripheral nerve injuries are common in Europe; however, the treatment techniques may lead to disabilities. This study aimed to evaluate the effect of tacrolimus use on the capacity of the epineural sheath graft ... -
The Effect of Virus-Specific Vaccination on Laboratory Infection Markers of Children with Acute Rotavirus-Associated Acute Gastroenteritis
(Mdpi, 2023)Objective: Rotavirus (RV) is one of the most common and important causes of acute gastroenteritis (AGE) in newborns and children worldwide. The aim of this study was to evaluate the effect of the RV vaccine on the natural ... -
Effects of Probiotic Bacteria on Central Neuronal Activation in Experimental Colitis
(National Library of Medicine, 2022)Background: Brain–gut axis dysregulation is observed in inflammatory bowel disease. However, the effect of altered gut flora on neuroimmunomodulation and its role in the pathogenesis of inflammatory bowel disease are ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an In Vitro Glioblastoma Model
(Elsevier Science Inc, 2019)BACKGROUND: The anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. The combined effect of EA with bevacizumab (BEV), a common drug ... -
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy
(Verduci Publisher, 2023)Objective: Oxidative stress and hypoxia play an important role in the pathogenesis of various cardiovascular diseases. We aimed to evaluate the effectiveness of sacubitril/valsartan (S/V) and Empagliflozin (EMPA) on ... -
Evaluating the Oncological and Functional Outcomes in 167 Patients Undergoing Laparoscopic Radical Prostatectomy: Could Laparoscopy Still be a Viable Option in Suitable Patients?
(MARY ANN LIEBERT, INC, 2024)Aim: To evaluate the oncological and functional outcomes of 167 patients who underwent laparoscopic radical prostatectomy (LRP). Materials and Methods: The retrospective study included 167 patients who were treated with ... -
Evaluation of Cytotoxicity and Antibacterial Effect of Different Types of Mineral Trioxide Aggregate
(Galenos Publishing House, 2023)Objective: Mineral trioxide aggregate (MTA) has been used as a filling material in endodontic procedures over decades. The newer formulations of MTA were launched in the dental market and their cytotoxic, proliferative and ...
