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Çocuklarda Nazofarengeal Streptococcus pneumoniae Taşıyıcılığı ve Penisilin Direnci
(2018)Amaç Penisiline dirençli suşların varlığı ve çoklu ilaç direncinin ortaya çıkması pnömokokların neden olduğu enfeksiyonların tedavisini zorlaştırmaktadır. Araştırmamızın amacı sağlıklı çocuklarda Streptococcus pneumoniae ... -
Akut Kolesistit Tanısında İnflamasyon Belirteçlerinden Nötrofillenfosit ve Trombosit-lenfosit Oranlarının C-reaktif protein Düzeyine Üstünlüğü Var mı?
(2019)Amaç: Akut kolesistit acil servis ve genel cerrahi polikliniklerinde sık tanı alan hastalıklardandır. İnflamasyon derecesi hastalığın morbidite ve mortalitesi üzerine etkilidir. Bu çalışmada inflamasyon derecesini ölçmede; ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
(Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an In Vitro Glioblastoma Model
(Elsevier Science Inc, 2019)BACKGROUND: The anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. The combined effect of EA with bevacizumab (BEV), a common drug ... -
Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms
(Aves, 2020)Background/Aims: Astaxanthin (ATX) is a naturally occurring carotenoid and a potent antioxidant. Various anti-inflammatory effects of ATX have been examined. We aimed to investigate the protective effect of ATX and its ... -
The effect of nitric oxide, endothelial nitric oxide synthetase, and asymmetric dimethylarginine in hemorrhoidal disease
(Assoc Medica Brasileira, 2020)AIM: The aim of this study was to examine the roles of nitric oxide (NOx), endothelial nitric oxide synthetase (eNOS), and asymmetric dimethylarginine (ADMA), which is the major endogenous inhibitor of nitric oxide synthases ... -
Can the risk of anal fistula development after perianal abscess drainage be reduced?
(Assoc Medica Brasileira, 2020)OBJECTIVE: Perianal abscesses are frequently seen in clinical practice, and perianal fistulas develop in 30%-50% of cases after treatment. This study investigated whether the type of dressing applied after abscess drainage ... -
The Effectiveness of Jet (Needle-Free) Injector to Provide Anesthesia in Child Circumcision under Local Anesthesia
(Taylor and Francis Ltd, 2020)Objective: In our study, we aimed to evaluate the effectiveness of a needle-free (jet) injector in local anesthesia for circumcision. Materials and Methods: A total of 64 children were divided into two groups as jet injector ... -
Alkaline Phosphatase is not Associated with Insulin Resistance: A Retrospective Cross-Sectional Study
(2020)Background: Many epidemiologic studies suggested that vitamin D deficiency is associated with obesity but the relationship between obesity and alkaline phosphatase (ALP) is controversial. In this study association ... -
Therapeutic Potential of Essential Oil of Melaleuca Quinquenervia (Myrtaceae) in a Rat Model of Ethanol-Induced Peptic Ulcer
(African Journals Online, 2021)Purpose: To evaluate the effects of M. quinquenervia extract on ethanol-induced peptic ulcer in rats. Methods: The following three groups of (n = 6) Sprague Dawley rats were included in this study: vehicle (C), ... -
Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects
(Acta Cırúrgıca Brasıleıra, 2021)Purpose: To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of esophageal damage and stricture formation due to esophageal caustic burns in rat model comparing with prednisolone. Methods: Caustic ... -
Investigating antimicrobial features and drug interactions of sedoanalgesics in intensive care unit: an experimental study
(International Association of Physical Chemists, 2021)Study Objective: Aim of this study was to evaluate antimicrobial effects and interaction between analgesic combinations of fentanyl citrate, dexmedetomidine hydrochloride and tramadol hydrochloride on Staphylococcus ... -
Effect of Tacrolimus on Peripheral Nerve Regeneration in Allograft Transplantation: A Light and Electron Microscopic Study
(Baskent Unıv, 2021)Objectives: Peripheral nerve injuries are common in Europe; however, the treatment techniques may lead to disabilities. This study aimed to evaluate the effect of tacrolimus use on the capacity of the epineural sheath graft ... -
Evaluation of the aortic velocity propagation, epicardial fat thickness, and carotid intima-media thickness in patients with subclinical hypothyroidism
(IMR Press, 2021)Subclinical hypothyroidism (SH) is associated with hemodynamic and metabolic abnormalities that cause endothelial dysfunction and atherosclerotic cardiovascular diseases. Aortic velocity propagation (AVP), epicardial fat ... -
Endoscopic Hernia Repair: A Novel Technique for the Repair of Inguinal Hernia in a Cadaver Model
(LIPPINCOTT WILLIAMS & WILKINS, 2021)Amaç: Kasık fıtığının laparoskopik onarımı için uzun zamandan beri total ekstraperitoneal ve transabdominal preperitoneal fıtık onarımı teknikleri uygulanmaktadır. Ancak genel anestezi gerektirmesi, olumsuz kozmetik sonuçlar ... -
The Effectiveness of Caudal Block with Low Doses of Dexmedetomidine and Pethidine in Transrectal Prostate Biopsy: Preliminary Results
(Taylor and Francis Ltd., 2021)Purpose: To evaluate the effectiveness of caudal block (CB) using dexmedetomidine and pethidine instead of local anesthesia (LA) for prostate needle biopsy and the effect of CB on urinary retention. Material and Methods: ... -
The Potential Therapeutic Effects of Agmatine, Methylprednisolone, and Rapamycin on Experimental Spinal Cord Injury
(Royan Institute (ACECR), 2021)Amaç: Omurilik yaralanmasında (SCI), birincil mekanik hasar nöroinflamatuar bir yanıta yol açar ve ikincil nöronal hasar, reaktif oksijen türlerinin (ROS) salınmasına yanıt olarak ortaya çıkar. Enflamasyonun baskılanmasına ... -
Frequency of frontotemporal dementia-related gene variants in Turkey
(Elsevier Science İnc, 2021)Frontotemporal demansın (FTD) klinik heterojenliği gibi genetik temeli de çeşitlidir ve hastalık patogenezinde çok sayıda moleküler yolakların rol oynadığı düşünülmektedir. Bu çalışmada FTD ile ilişkili genler, 175 indeks ... -
Association between the Trp64Arg polymorphism of the ADRB3 gene and overactive bladder
(WILEY HOBOKEN, 2021)Arka Plan Beta(3)-adrenerjik reseptör (ADRB3), insan detrüsör kas fonksiyonunun düzenlenmesinde çok önemlidir. ADRB3 geninin iyi bilinen triptofan64arginin polimorfizmi, reseptörün adrenalin ve noradrenalin dahil olmak ... -
The Growth Factor/cytokine Midkine May Participate in Cytokine Storm and Contribute to the Pathogenesis of Severe Acute Respiratory Syndrome Coronavirus 2-infected Patient
(The Egyptian Journal of Bronchology, 2021)Background The current coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged in Wuhan, China, and has rapidly become a global challenge, creating ...