Browsing by Department "İstanbul Atlas Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü"
Now showing items 1-17 of 17
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Alkaline Phosphatase is not Associated with Insulin Resistance: A Retrospective Cross-Sectional Study
(2020)Background: Many epidemiologic studies suggested that vitamin D deficiency is associated with obesity but the relationship between obesity and alkaline phosphatase (ALP) is controversial. In this study association ... -
Antitumor activity of irinotecan with ellagic acid in C6 glioma cells
(Revista da Associação Médica Brasileira, 2022)OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, ... -
Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms
(Aves, 2020)Background/Aims: Astaxanthin (ATX) is a naturally occurring carotenoid and a potent antioxidant. Various anti-inflammatory effects of ATX have been examined. We aimed to investigate the protective effect of ATX and its ... -
Circulating mir-132, mir-146a, mir-222, and mir-320 expression in differential diagnosis of women with polycystic ovary syndrome
(Acta Endocrinologica-Bucharest, 2022)Purpose. The aim of the study was to investigate whether the circulating miR-132, miR-146a, miR-222, and miR-320 levels are used in the differential diagnosis of women with polycystic ovary syndrome (PCOS) and ... -
The clinical significance of circulating mir-21, mir-142, mir-143, and mir-146a ın patients with prostate cancer
(Society of Medical Biochemists of Serbia, 2022)Background: Prostate cancer (PCa) is the most common type of solid tissue cancer among men in western countries. In this study, we determined the levels of circulating miR-21, miR-142, miR-143, miR-146a, and RNU 44 levels ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
(Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects
(Acta Cırúrgıca Brasıleıra, 2021)Purpose: To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of esophageal damage and stricture formation due to esophageal caustic burns in rat model comparing with prednisolone. Methods: Caustic ... -
Effects of Probiotic Bacteria on Central Neuronal Activation in Experimental Colitis
(National Library of Medicine, 2022)Background: Brain–gut axis dysregulation is observed in inflammatory bowel disease. However, the effect of altered gut flora on neuroimmunomodulation and its role in the pathogenesis of inflammatory bowel disease are ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an In Vitro Glioblastoma Model
(Elsevier Science Inc, 2019)BACKGROUND: The anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. The combined effect of EA with bevacizumab (BEV), a common drug ... -
Importance of oxidative stress in the evaluation of acute pulmonary embolism severity
(BMC Pulmonary Medicine, 2022)Background: Pulmonary embolism (PE) is a common and potentially life-threatening disorder. Our study was aimed to investigate whether oxidative stress markers can be used as clinical markers in the evaluation of acute ... -
Investigating antimicrobial features and drug interactions of sedoanalgesics in intensive care unit: an experimental study
(International Association of Physical Chemists, 2021)Study Objective: Aim of this study was to evaluate antimicrobial effects and interaction between analgesic combinations of fentanyl citrate, dexmedetomidine hydrochloride and tramadol hydrochloride on Staphylococcus ... -
Investigation of the effects of total oxidative stress and total antioxidant capacity on the prognosis in patients with chronic viral hepatitis b
(2022)Objectives: Experimental studies showed the role of oxidative stress in cell destruction and DNA damage in chronic viral hepatitis, In this study, oxidative stress was measured in various clinical forms of chronic ... -
Relationship between serum sialic acid levels and prolidase activity with airflow obstruction in patients with COPD
(Lippincott Williams & Wilkins, 2022)Our aim in this study was to evaluate the prognostic significance of sialic acid (SA) and prolidase activity and to evaluate the association between airflow obstruction severity and these parameters in chronic obstructive ... -
The role of S100A12 and Toll-like receptor 4 in assessment of disease activity in familial Mediterranean fever and juvenile idiopathic arthritis
(Wiley Online Library, 2022)Objective Our aim was to investigate the possible relationship between the serum S100A12 and Toll-like receptor 4 (TLR4) levels, and the activity of familial Mediterranean fever (FMF) and juvenile idiopathic arthritis (JIA) ... -
S100 Protein Family in Rheumatological Diseases
(GAZI MEDICAL JOURNAL, 2022)Inflammation in joint tissues is one of the causes of early mortality in rheumatological diseases. In fact, inflammation process is followed by cell infiltration, synovial tissue ... -
Serum and intestinal tissue zonulin levels in the evaluation of intestinal permeability in rats with acute pancreatitis
(2022)To evaluate the eff ects on malondialdehyde (MDA), superoxide dismutase (SOD), lipid hydroperoxide (LOOH), glutathione (GSH) levels as oxidative stress markers, zonulin levels, and histopathological findings of experimental ... -
Therapeutic Potential of Essential Oil of Melaleuca Quinquenervia (Myrtaceae) in a Rat Model of Ethanol-Induced Peptic Ulcer
(African Journals Online, 2021)Purpose: To evaluate the effects of M. quinquenervia extract on ethanol-induced peptic ulcer in rats. Methods: The following three groups of (n = 6) Sprague Dawley rats were included in this study: vehicle (C), ...
