Bölüm "İstanbul Atlas Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için listeleme
Toplam kayıt 84, listelenen: 1-20
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Activation of TRESK Channels Ameliorates Pain and Neurogenic Inflammation in a Nitroglycerin-Induced Migraine Model in Rats
(Wiley, 2023)We investigated effects of activation of TRESK channels by selective activator cloxyquin on excitotoxic-induced brain injury and neuroinflammation involving brain mast cells and inflammatory cytokines in neonatal rats. ... -
Alkaline Phosphatase is not Associated with Insulin Resistance: A Retrospective Cross-Sectional Study
(2020)Background: Many epidemiologic studies suggested that vitamin D deficiency is associated with obesity but the relationship between obesity and alkaline phosphatase (ALP) is controversial. In this study association ... -
Alterations in expression of phosphatase and tensin homologous (PTEN) gene analyzed in the bronchial lavage samples of non-small cell lung cancer patients
(Bayrakol Medical Publishing, 2024)Aim: In this study, we aimed to analyze the expression of the Phosphatase and Tensin Homologous gene (PTEN) by interphase-fluorescence in situ-hybridization (iFISH), and localization and immunoreactivity of PTEN by ... -
Anticancer drug doxorubicin (DOX) loading performance of functionalized polyaniline (PANI) surface with active carbon
(SPRINGER, 2023)The study was based on surface functionalization of conductive PANI (polyaniline) polymer for drug delivery systems. Specifically, an electrochemical polymerization technique was performed for the synthesis of PANI layers ... -
Antitumor activity of irinotecan with ellagic acid in C6 glioma cells
(Revista da Associação Médica Brasileira, 2022)OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, ... -
Assessing the protective effects of chard on valproic acid-induced pancreatic complications
(NATL INST SCIENCE COMMUNICATION-NISCAIR, 2024)Valproic acid (VPA) treatment is known to potentially cause adverse effects, notably as the most common cause of druginduced acute pancreatitis. It is crucial to balance the therapeutic benefits and potential major side ... -
Assessment of sensitivity to the anesthesia in a diabetic rat model
(VERDUCI PUBLISHER, 2023)OBJECTIVE: Diabetes mellitus and glucose regulation are important in decid-ing on surgical intervention in pre-surgical as-sessments. In our study, we aimed to investigate the correlations between the induction time of ... -
The Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and Prediabetes
(Mdpi, 2023)In this study, we aimed to reveal the pro-inflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabetes. We recruited 84 prediabetes ... -
Association between serum irisin concentration and ischemic stroke: From etiology to clinic
(Society of Medical Biochemists of Serbia, 2022)Background: To investigate the relationship between irisin levels in serum and classification of subtype of acute ischemic stroke, National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Score (mRS) at the ... -
The Associations between Asprosine, Clusterin, Zinc Alpha-2-Glycoprotein, Nuclear Factor Kappa B, and Peroxisome Proliferator-Activated Receptor Gamma in the Development of Complications in Type 2 Diabetes Mellitus
(MDPI, 2024)Objectives: The aim of this study was to investigate the circulating levels of asprosin, clusterin, zinc-alpha-2-glycoprotein (ZAG), nuclear factor-kappa B (NF-kappa B), and peroxisome proliferator-activated receptor-gamma ... -
Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms
(Aves, 2020)Background/Aims: Astaxanthin (ATX) is a naturally occurring carotenoid and a potent antioxidant. Various anti-inflammatory effects of ATX have been examined. We aimed to investigate the protective effect of ATX and its ... -
Can Acellular Dermal Matrix and Kombucha Cellulose Membrane Be Used in Calvarial Reconstruction?
(Galenos Publ House, 2023)Amaç: Amacımız aselüler dermal matriks (ADM) ve Kombucha membranının (KM) kalvarial dura onarımında uygulanabilirliğini araştırmaktı. malzeme kusurları. Yöntemler: Wistar sıçanları üzerinde yapılan bir çalışmada altı ... -
Can circulating oxidative stress-related biomarkers be used as an early prognostic marker for COVID-19?
(Frontiers Media Sa, 2023)Arka Plan Oksidatif stres birçok hastalığın patogenezinde önemli bir rol oynar. Bu çalışma, yeni COVİD-19 hastalarında nükleer faktör kappa B (NF-kappa B) ile oksidatif stres arasındaki ilişkiyi ve hastalığın ciddiyetini ... -
Circulating mir-132, mir-146a, mir-222, and mir-320 expression in differential diagnosis of women with polycystic ovary syndrome
(Acta Endocrinologica-Bucharest, 2022)Purpose. The aim of the study was to investigate whether the circulating miR-132, miR-146a, miR-222, and miR-320 levels are used in the differential diagnosis of women with polycystic ovary syndrome (PCOS) and ... -
The clinical significance of circulating mir-21, mir-142, mir-143, and mir-146a ın patients with prostate cancer
(Society of Medical Biochemists of Serbia, 2022)Background: Prostate cancer (PCa) is the most common type of solid tissue cancer among men in western countries. In this study, we determined the levels of circulating miR-21, miR-142, miR-143, miR-146a, and RNU 44 levels ... -
CLINICAL SIGNIFICANCE OF SERUM SYNAPTOPHYSIN-LIKE 1 PROTEIN LEVELS IN BREAST CANCER
(SOC MEDICAL BIOCHEMISTS SERBIA, 2024)Background: Mammography, used for breast cancer (BC) screening, has limitations such as decreased sensitivity in dense breasts. Currently used tumor markers are insufficient in diagnosing breast cancer. In this study, we ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
(Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Comparable ongoing pregnancy and pregnancy loss rates in natural cycle and artificial cycle frozen embryo transfers with intensive method-specific luteal phase support; a retrospective cohort study
(ELSEVIER MASSON, CORP OFF, 2024)Study objective: The absence of corpus lutea in artificial cycle (AC) frozen embryo transfers (FET) may increase the chances of pregnancy loss. In this retrospective cohort study, the efficacy of AC endometrial preparation ... -
Comparing fractional microneedle radiofrequency and fractional CO2 laser for striae distensae treatment: a systematic review and meta-analysis
(SPRINGER LONDON LTD, 2024)Striae distensae (SD) are a prevalent dermatological concern of women and approximately 90% of pregnant women experience these stretch marks. Fractional microneedle radiofrequency (FMR) and fractional CO2 laser (FCL) have ... -
Comparison of Selenic Acid and Pyruvic Acid-Loaded Silver Nanocarriers Impact on Colorectal Cancer Viability
(SPRINGER/PLENUM PUBLISHERS, 2023)Colorectal cancer (CRC) is a leading cause of morbidity and death worldwide. As current cancer drugs are ineffective, new solutions are being sought in other fields, including nanoscience. Similarly, silver nanoparticles ...
