Bölüm "İstanbul Atlas Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" PubMed İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 32, listelenen: 1-20
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Antitumor activity of irinotecan with ellagic acid in C6 glioma cells
(Revista da Associação Médica Brasileira, 2022)OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, ... -
Assessment of sensitivity to the anesthesia in a diabetic rat model
(VERDUCI PUBLISHER, 2023)OBJECTIVE: Diabetes mellitus and glucose regulation are important in decid-ing on surgical intervention in pre-surgical as-sessments. In our study, we aimed to investigate the correlations between the induction time of ... -
The Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and Prediabetes
(Mdpi, 2023)In this study, we aimed to reveal the pro-inflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabetes. We recruited 84 prediabetes ... -
Association between serum irisin concentration and ischemic stroke: From etiology to clinic
(Society of Medical Biochemists of Serbia, 2022)Background: To investigate the relationship between irisin levels in serum and classification of subtype of acute ischemic stroke, National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Score (mRS) at the ... -
Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms
(Aves, 2020)Background/Aims: Astaxanthin (ATX) is a naturally occurring carotenoid and a potent antioxidant. Various anti-inflammatory effects of ATX have been examined. We aimed to investigate the protective effect of ATX and its ... -
Can circulating oxidative stress-related biomarkers be used as an early prognostic marker for COVID-19?
(Frontiers Media Sa, 2023)Arka Plan Oksidatif stres birçok hastalığın patogenezinde önemli bir rol oynar. Bu çalışma, yeni COVİD-19 hastalarında nükleer faktör kappa B (NF-kappa B) ile oksidatif stres arasındaki ilişkiyi ve hastalığın ciddiyetini ... -
CLINICAL SIGNIFICANCE OF SERUM SYNAPTOPHYSIN-LIKE 1 PROTEIN LEVELS IN BREAST CANCER
(SOC MEDICAL BIOCHEMISTS SERBIA, 2024)Background: Mammography, used for breast cancer (BC) screening, has limitations such as decreased sensitivity in dense breasts. Currently used tumor markers are insufficient in diagnosing breast cancer. In this study, we ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
(Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Could Long Non-Coding RNA MEG3 and PTENP1 Interact with miR-21 in the Pathogenesis of Non-Alcoholic Fatty Liver Disease?
(MDPI, 2023)NAFLD is the most common cause of chronic liver disease worldwide. The miRNAs and lncRNAs are important endogenous ncRNAs families that can regulate molecular mechanisms. The aim of this study was to analyze the miRNA and ... -
Could Prior COVID-19 Affect the Neutralizing Antibody after the Third BNT162b2 Booster Dose: A Longitudinal Study
(MDPI, 2023)Aşılama, devam eden COVID-19 salgını sırasında hastalığın yayılmasını önlemek için temel bir halk sağlığı önlemidir. Konakçının geliştirdiği immün yanıt veya aşının oluşturduğu immünolojik yanıtın devam etmesi, salgının ... -
Effect of Tacrolimus on Peripheral Nerve Regeneration in Allograft Transplantation: A Light and Electron Microscopic Study
(Baskent Unıv, 2021)Objectives: Peripheral nerve injuries are common in Europe; however, the treatment techniques may lead to disabilities. This study aimed to evaluate the effect of tacrolimus use on the capacity of the epineural sheath graft ... -
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats
(MASHHAD UNIV MED SCIENCES, 2024)Objective(s): We aimed to investigate the levels of transient receptor potential melastatin (TRPM) gene expression, and the antioxidant and histopathologic effect of thymoquinone (Tmq) in the hepatic I/R rat model. Materials ... -
The Effect of Virus-Specific Vaccination on Laboratory Infection Markers of Children with Acute Rotavirus-Associated Acute Gastroenteritis
(Mdpi, 2023)Objective: Rotavirus (RV) is one of the most common and important causes of acute gastroenteritis (AGE) in newborns and children worldwide. The aim of this study was to evaluate the effect of the RV vaccine on the natural ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an In Vitro Glioblastoma Model
(Elsevier Science Inc, 2019)BACKGROUND: The anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. The combined effect of EA with bevacizumab (BEV), a common drug ... -
The Epidemiology of Deficiency of Vitamin B12 in Preschool Children in Turkey
(MDPI, 2023)Background: Vitamin B12 is a water-soluble vitamin with important cellular functions; it is an essential vitamin. The aim of this study is to determine the B12 levels of children in the period from the 6th month when ... -
Evaluation of serum interleukin-38 levels in different radiographic grades of idiopathic knee osteoarthritis
(Mary Ann Liebert, INC, 2021)Bu çalışmanın amacı farklı radyografik derecelerde diz osteoartriti (OA) olan hastalarda interlökin-1 beta (IL-1 beta), IL-1Ra, IL-36 ve IL-38 düzeyleri ile hs-CRP düzeylerini değerlendirmektir. Sağlıklı bireylerle ... -
In vitro effects of heparin-binding epidermal growth factor on adhesion stage of implantation
(EDITURA ACAD ROMANE, 2023)A member of the epidermal growth factor (EGF) family, the heparin-binding EGF (HB-EGF) is expressed in the uteri of both humans and mice during the implantation process. To study the effects of HB-EGF on adhesion stage, ... -
A Longitudinal Study in Turkiye of Host Ability to Produce Antibodies following a Third Homologous BNT162b2 Vaccination
(MDPI, 2023)Obesity is a multifaceted, complex condition that has negative impacts on one's health. There are conflicting reports regarding the COVID-19 vaccine's ability to induce antibody formation in obese people. Our study aimed ... -
Maternal serum preptin levels in the pathogenesis and diagnosis of gestational diabetes mellitus
(Society of Medical Biochemists of Serbia, 2023)Background: Gestational diabetes mellitus (GDM) is a metabolic disorder that occurs during pregnancy that increases both maternal and fetal mortality and morbidity. It was investigated whether there is a change in circulating ... -
Neutralization of Wild-Type and Alpha SARS-CoV-2 Variant by CoronaVac® Vaccine and Natural Infection- Induced Antibodies
(Springer, 2023)One of the immune responses desired to be achieved by SARS-CoV-2 vaccination is to create neutralizing antibodies (nAbs), thus preventing the development and spread of infection. The aim of this study was to investigate ...