Yazar "Uzun, Hafize" için listeleme
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Original contribution: sleeve gastrectomy reduces soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) levels in patients with morbid obesity
Taşkın, Halit Eren; Kocael, Ahmet; Kocael, Pinar; Zengin, Kagan; Al, Muzaffer; Sozer, Volkan; Uzun, Hafize (Springer, 2022)Background Early diagnosis of subclinical cardiovascular disease (CVD) in patients with morbid obesity is important. We investigated the effects of sleeve gastrectomy (SG) on serum soluble lectin-like oxidized low-density ... -
Prediction of Preterm Delivery Using Serum Ischemia Modified Albumin, Biglycan, and Decorin Levels in Women with Threatened Preterm Labor
Bıyık, İsmail; Soysal, Cenk; İnce, Özlem Ulaş Onur; Durmuş, Sinem; Öztaş, Efser; Keskin, Nadi; Işıklar, Özben Özden; Karaağaç, Oğuz Han; Gelişgen, Remise; Uzun, Hafize (Georg Thieme Verlag KG, 2023)Objective The serum ischemia modified albumin (IMA), biglycan, and decorin levels of pregnant women who were hospitalized for threatened preterm labor were measured.Methods Fifty-one consecutive pregnant women with a single ... -
Ranolazine exhibits anti-inflammatory and antioxidant activities in H9c2 cardiomyocytes
Doğan, Zeki; Durmus, S.; Ergun, D. D.; Gelişgen, Remise; Uzun, Hafize (Verduci Publisher, 2023)OBJECTIVE: The aim of this study was to evaluate the effectiveness of ranola-zine on hypoxia-inducible factor-1 alpha (HIF-1 alpha) and oxidative stress in H9c2 cardiomyocyte cells.MATERIALS AND METHODS: We have as-sessed ... -
The relationship between hematological indices as indicators of inflammation and 25-hydroxyvitamin D3 status in newborns
Uzun, Hafize; Elgörmüş, Yusuf; Okuyan, Ömer (National Library of Medicine, 2023)Arka Plan Yenidoğanlarda hematolojik parametreler ile D vitamini durumu arasındaki ilişki hakkında hala pek çok şey bilinmemektedir. Çalışmanın amacı 25(OH)D3 (D vitamini) durumu ile yeni tanımlanmış sistemik inflamatuar ... -
Relationship between serum sialic acid levels and prolidase activity with airflow obstruction in patients with COPD
Uysal, Pelin; Teksöz, Duygu; Aksan, Hülya; Durmuş, Sinem; Gelişgen, Remise; Şimşek, Gönül; Uzun, Hafize (Lippincott Williams & Wilkins, 2022)Our aim in this study was to evaluate the prognostic significance of sialic acid (SA) and prolidase activity and to evaluate the association between airflow obstruction severity and these parameters in chronic obstructive ... -
The Role of Glycogen Synthase Kinase-3β in the Zinc-Mediated Neuroprotective Effect of Metformin in Rats with Glutamate Neurotoxicity
Oruc, Aykut; Oruc, Kadriye Yagmur; Yanar, Karolin; Mengi, Murat; Caglar, Aysel; Kurt, Bahar Öztürk; Altan, Mehmet; Sönmez, Osman Fuat; Cakatay, Ufuk; Uzun, Hafize; Simsek, Gönül (Wiley, 2023)Metformin has been suggested to have protective effects on the central nervous system, but the mechanism is unknown. The similarity between the effects of metformin and the inhibition of glycogen synthase kinase (GSK)-3β ... -
The role of laparoscopic sleeve gastrectomy on inflammatory parameters n morbidly obese patients
Ergun, S.; Ergun, D. D.; Akıncı, O.; Taşkın, Halit Eren; Simsek, Gönül; Taşkın, M.; Uzun, Hafize (Elsevier Masson, Corp Off, 2022)Background: Obesity is an excessive increase in body fat mass and triggers chronic inflammation which causes increased fat accumulation in the visceral fat tissue. The aim of this study was to analyze serum zinc (Zn), ... -
The Role of NF-κB, PPAR-α, and PPAR-γ in Older Adults with Metabolic Syndrome
Demirağ, Filiz; Yavuzer, Serap; Cengiz, Mahir; Yavuzer, Hakan; Kara, Zehra; Ayvacı, Adnan; Avcı, Suna; Yürüyen, Mehmet; Uzun, Hafize; Altıparmak, Mehmet Rıza (Georg Thieme Verlag KG, 2023)The etiopathogenesis of metabolic syndrome (MetS) has not been fully understood yet, and chronic low-grade inflammation is thought to be associated with the development of complications related to MetS. We aimed to investigate ... -
Role of Reelin and Zinc in the Pathogenesis of D-Glutamic Acid-Induced PAH
Oruç, Kadriye Yağmur; Oruç, Aykut; Altan, Mehmet; Sönmez, Osman Fuat; Yanar, Karolin; Kepil, Nuray; Mengi, Murat; Çakatay, Ufuk; Uzun, Hafize; Şimşek, Gönül (WILEY, 2023)Supplement:730 Special Issue:SI Meeting Abstract:PC-075 -
Serum and intestinal tissue zonulin levels in the evaluation of intestinal permeability in rats with acute pancreatitis
Yıldız, Abdullah; Kundaktepe, Berrin Papila; Yüksekdağ, Sema; Durmuş, Sinem; Silav, Zuhal Kuş; Gelişgen, Remise; Ünal, Ethem; Uzun, Hafize (2022)To evaluate the eff ects on malondialdehyde (MDA), superoxide dismutase (SOD), lipid hydroperoxide (LOOH), glutathione (GSH) levels as oxidative stress markers, zonulin levels, and histopathological findings of experimental ... -
Significance of Cyclooxgenase-2 gene polymorphism and related miRNAs in pulmonary arterial hypertension
Durmuş, Sinem; Atahan, Ersan; Avcı Kılıçkıran, Burçak; Önal, Burak; Çakatay, Ufuk; Gelişgen, Remise; Uzun, Hafize (Elsevier, 2022)Background: Pulmonary arterial hypertension (PAH) is a rare disease with a poor prognosis. The suppression of cyclooxygenase-2 (COX-2) expression has been known to impair vascular function in endothelial cells; however, ... -
Significance of Plasma Irisin, Adiponectin, and Retinol Binding Protein-4 Levels as Biomarkers for Obstructive Sleep Apnea Syndrome Severity
Fazlıoğlu, Nevin; Uysal, Pelin; Durmuş, Sinem; Yurt, Sibel; Gelişgen, Remise; Uzun, Hafize (MDPI, 2023)Objective: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder that is caused by the reduction or cessation of airflow in the upper airway. Irisin, retinol-binding protein-4 (RBP-4), and adiponectin are the ... -
Thrombospondin 1 and Nuclear Factor Kappa B Signaling Pathways in Non-alcoholic Fatty Liver Disease
Ekinci, İskender; Dumur, Şeyma; Uzun, Hafize; Anataca, Gulden; Yalcinkaya, İsa; Büyükkaba, Mitat (Medıcal Unıv Press, 2022)Amaç: Alkolsüz yağlı karaciğer hastalığında (NAFLD) dolaşımdaki trombospondin-1 (TSP-1) ve nükleer faktör kappa B'yi (NF-κB) bu sinyal yolaklarını karaciğerin inflamatuar ve fibrojenik süreçlerine entegre etmek amacıyla ...