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Protective effect of oxytocin through its anti-inflammatory and antioxidant role in a model of sepsis-induced acute lung injury: Demonstrated by CT and histological findings

Sever, I. H.; Özkul, Bahattin; Erisik Tanriover, D.; Ozkul, O.; Elgörmüş, Çağrı Serdar; Gur, S. G.; Sogut, I. (Taylor & Francis Inc, 2021)

Purpose: Although several studies demonstrate the anti-inflammatory effect of oxytocin in different pathophysiological processes, there are limited data describing the impact of oxytocin on acute respiratory distress ...

Activation of TRESK Channels Ameliorates Pain and Neurogenic Inflammation in a Nitroglycerin-Induced Migraine Model in Rats

Torun, İbrahim Ethem; Kilinc, Yasemin Bakanoğlu; Kilinc, Erkan; Töre, Fatma (Wiley, 2023)

We investigated effects of activation of TRESK channels by selective activator cloxyquin on excitotoxic-induced brain injury and neuroinflammation involving brain mast cells and inflammatory cytokines in neonatal rats. ...

The Role of NF-κB, PPAR-α, and PPAR-γ in Older Adults with Metabolic Syndrome

Demirağ, Filiz; Yavuzer, Serap; Cengiz, Mahir; Yavuzer, Hakan; Kara, Zehra; Ayvacı, Adnan; Avcı, Suna; Yürüyen, Mehmet; Uzun, Hafize; Altıparmak, Mehmet Rıza (Georg Thieme Verlag KG, 2023)

The etiopathogenesis of metabolic syndrome (MetS) has not been fully understood yet, and chronic low-grade inflammation is thought to be associated with the development of complications related to MetS. We aimed to investigate ...

Lymphocyte to monocyte ratio may predict increased carotid intima-media thickness in patients with subclinical hypothyroidism

Yurtdaş, Mustafa; Aşoglu, Ramazan; Özaydın, Adnan; Doğan, Zeki (IOS PRESS, 2021)

AMAÇ: İnflamasyonun ateroskleroz patogenezinde önemli bir rolü vardır. Lenfosit-monosit oranı (LMR) inflamasyonun bir göstergesi olarak kabul edilmektedir. AMAÇ: Amacımız, subklinik hipotiroidizmde (SubHT) karotis intima-media ...

Demonstration of ameliorating effect of vardenafil through its anti-inflammatory and neuroprotective properties in autism spectrum disorder induced by propionic acid on rat model

Özkul, Bahattin; Urfalı, Furkan Ertürk; Sever, İbrahim Halil; Bozkurt, Mehmet Fatih; Sogut, Ibrahim; Elgörmüş, Çağrı Serdar; Erbaş, Oytun (Taylor & Francis Ltd, 2022)

Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology. In this study, we aimed to determine the ameliorating effects of vardenafil in the ASD rat model induced by propionic acid ...

The Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and Prediabetes

Fenercioglu, Aysen Kutan; Gonen, Mustafa Sait; Uzun, Hafize; Sipahioglu, Nurver Turfaner; Can, Gunay; Tas, Ebru; Kara, Zehra (Mdpi, 2023)

In this study, we aimed to reveal the pro-inflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabetes. We recruited 84 prediabetes ...