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Quantitative Evaluation of Lung Parenchyma Changes after Treatment in COVID-19 Pneumonia with Volumetric Study in Computed Tomography

Özkul, Bahattin; Urfalı, Furkan Ertürk; Asil, Kıyasettin (Clinical and Experimental Health Sciences, 2022)

Objective COVID-19 pandemic, causing approximately 3 million deaths over worldwide, still continues. Effect of COVID-19 pneumonia after treatment on the lungs still not know. Although widely using computed tomography (CT) ...

Short term protective effect of digitoxin in sepsis-induced acute lung injury

Bora, Ejder Saylav; Erdoğan, Mümin Alper; Özkul, Bahattin; Sever, İbrahim Halil; Söğüt, İbrahim; Hürdağ, Canan; Erbaş, Oytun (Tech Science Press, 2022)

Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light its effect ...

Indirect evaluation of amyloid deposition by ultrasonography and its relationship with MEFV gene mutation in FMF patients

Urfalı, Mine; Yılmaz, Gürkan; Özkul, Bahattin; Urfalı, Furkan Ertürk (Wiley Online Library, 2022)

ObjectiveThe most significant complication in familial mediterranean fever (FMF) patients is dysfunction and organ failure developing depending on amyloid deposition in organs. The golden standard for showing amyloid ...

Predicting the Overall Survival in Patients with Advanced Pancreatic Cancer by Calculating L3 Skeletal Muscle Index Derived from CT

Özkul, Bahattin; Ozkul, Ozlem; Bilir, Cemil (Bentham Scıence Publ LTD, 2022)

Background: Pancreatic cancer is mostly diagnosed in advanced stages, and treatment results are not satisfactory. L3 skeletal muscle index (SMI) has emerged as a prognostic factor in pancreatic cancer patients. We aimed ...

Protective effect of oxytocin through its anti-inflammatory and antioxidant role in a model of sepsis-induced acute lung injury: Demonstrated by CT and histological findings

Sever, I. H.; Özkul, Bahattin; Erisik Tanriover, D.; Ozkul, O.; Elgörmüş, Çağrı Serdar; Gur, S. G.; Sogut, I. (Taylor & Francis Inc, 2021)

Purpose: Although several studies demonstrate the anti-inflammatory effect of oxytocin in different pathophysiological processes, there are limited data describing the impact of oxytocin on acute respiratory distress ...

Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats

Erdoğan, Mümin Alper; Turk, Miray; Doganay, Gizem Dinler; Sever, İbrahim Halil; Özkul, Bahattin; Söğüt, İbrahim; Eroğlu, Ebru; Uyanikgil, Yigit; Erbaş, Oytun (Springer, 2023)

Recent research on placental, embryo, and brain organoids suggests that the COVID-19 virus may potentially affect embryonic organs, including the brain. Given the established link between SARS-CoV-2 spike protein and ...

Protective Effects of Ibudilast Against Cisplatin-Induced Hepatotoxicity and Nephrotoxicity Mediated by Prostacyclin Enhancement

Özkul, Özlem; Özkul, Bahattin; Erdoğan, Mümin Alper; Erbaş, Oytun (Asian Network for Scientific Information (ANSInet), 2023)

Background and Objective: Cisplatin, a prevalent chemotherapy drug, presents hepatotoxic and nephrotoxic side effects, this study explores ibudilast's potential protective effects against such damage via prostacyclin ...

Medroxyprogesterone acetate improves propionic acid-induced autism rat model and magnetic resonance spectroscopic correlation

Bozkurt, Mehmet Fatih; Bhayal, Muhammad Nasir; Sever, İbrahim Halil; Özkul, Bahattin; Erbaş, Oytun (Bangladesh Pharmacological Society, 2022)

The protective effect of medroxyprogesterone acetate on propionic acid induced autism in rats was evaluated. For this purpose, 30 rats were divided into three groups. The significant difference in the levels of IL-17 ...

PREDICTING NUCLEAR RENOGRAPHY BASED SPLIT RENAL FUNCTION IN LIVING DONOR TRANSPLANTATION WITH CT BASED MEASURED SPLIT RENAL VOLUMES

Özkul, Bahattin; Barlas, Ilhami Soykan; Sever, İbrahim Halil; Gur, Seray Gizem; Akın, Emin Barış (Wiley, 2021)

Neuroprotective effect of polyethylene Glycol (PEG-3350) on radiation-induced brain injury via membrane stabilization

Sever, I. H.; Özkul, Bahattin; Atasoy, Özüm; Cini, Nilsu; Bozkurt, Mehmet Fatih; Erdogan, M. A.; Yaprak, G; Erbaş, Oytun (IJRR - International Journal of Radiation Research, 2023)

Background: This research aims to evaluate whether polyethylene glycol (PEG), which can immediately repair neuronal membranes, will have a protective effect against radiation-induced brain injury (RIBI). Materials and ...