Browsing by Author "Doğan, Zeki"
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Assessment of subtle cardiac dysfunction induced by premature ventricular contraction using two-dimensional strain echocardiography and the effects of successful ablation
Doğan, Zeki; Erden, Emine Cakcak; Erden, İsmail; Bektaşoğlu, Gökhan (Elsevier España S.L.U., 2024)Introduction and objectives: We aimed to assess the effects of successful ablation on impaired left ventricular global longitudinal strain (LV-GLS) in patients with frequent premature ventricular contractions (PVCs). We ... -
Association between history of polymerase chain reaction-verified covid-19 ınfection and outcomes of subsequent st-elevation myocardial ınfarction
Doğan, Zeki; Erden, İsmail; Bektaşoğlu, Gökhan; Karabulut, Ahmet (Sage Publications Inc, 2022)While the acute phase of coronavirus disease 2019 (COVID-19) is associated with worsening cardiac outcomes, it is unclear whether it affects the outcome of patients with ST-segment elevation myocardial infarction (STEMI) ... -
The Association of Glomerular Filtration Rate With Echocardiographic Parameters in Chronic Kidney Disease
Özdemir, Mahmut; Asoğlu, Ramazan; Doğan, Zeki; Aladağ, Nesim; Akbulut, Tayyar; Yurtdaş, Mustafa (ELMER PRESS INC, 2021)Background: Cardiovascular disease (CVD) is the primary cause of mortality and morbidity in chronic kidney disease (CKD) patients. Aortic propagation velocity (APV), epicardial fat thickness (EFT) and carotid intima-media ... -
Brugada phenocopy associated with multiple psychotic drugs
Gül, Enes Elvin; Bektaşoğlu, Gökhan; Doğan, Zeki (Churchill Livingstone is an academic publisher, 2023)Brugada phenocopy (BrP) is a clinical condition characterized by transient ECG changes of Brugada syndrome (BrS), which can be due to various clinical conditions. We describe a case report of BrP due to psychotic drugs. -
Can additional information be obtained in the diagnosis of heart failure in type 2 diabetics by evaluating the hematological indices
Doğan, Zeki; Uzun, Hafize (INTERNATIONAL JOURNAL OF MEDICAL BIOCHEMISTRY, 2023)Objectives: The aim of the present study is to investigate whether hematological indices inflammatory parameters such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and lymphocyte-monocyte ratio ... -
Cardiovascular drugs and analysis of potential risk factors associated with mortality in severe coronavirus disease 2019 patients
Atabey, Rukiye Derin; Aladağ, Nesim; Şipal, Abdulcebbar; Akbulut, Tayyar; Doğan, Zeki; Özdemir, Mahmut (Revista da Associação Médica Brasileira, 2022)OBJECTIVES: Cardiovascular diseases are also considered to increase the risk of death in COVID-19 patients. However, real-world data concerning the risk factors for death in patients with severe COVID-19 still remain ... -
Circulating biomarkers associated with pyroptosis in the differential diagnosis of ST-segment elevation and non-ST-segment elevation myocardial infarction
Doğan, Zeki; Şenyiğit, Abdülhalim; Dümür, Şeyma; Mısırlıoğlu, Naile Fevziye; Uzun, Nedim; Aydın, Sümeyye Nur; Melekoğlu, Adem; Altınbilek, Ertuğrul; Çakatay, Ufuk; Uzun, Hafize (FRONTIERS MEDIA SA, 2025)Objectives To evaluate the biomarker value of NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3), gasdermin D (GSDMD), caspase-1, interleukin 1 beta (IL-1 beta), and IL-18 in the systemic circulation in ST-elevation ... -
Effect of dapagliflozin on oxidative stress in heart embryonic H9c2 cardiomyocytes
Doğan, Zeki; Uzun, Hafize (INTERNATIONAL JOURNAL OF MEDICAL BIOCHEMISTRY, 2024)Objectives: Dapagliflozin is a drug used to treat type 2 diabetes and is also used in certain heart failure and chronic kidney disease conditions. In this study, we investigated the effects of dapagliflozin (DAPA) on ... -
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy
Doğan, Zeki; Ergun, D. D.; Durmus, S.; Şahin, Hilal; Şentürk, G. E.; Gelişgen, Remise; Senyigit, A.; Uzun, Hafize (Verduci Publisher, 2023)Objective: Oxidative stress and hypoxia play an important role in the pathogenesis of various cardiovascular diseases. We aimed to evaluate the effectiveness of sacubitril/valsartan (S/V) and Empagliflozin (EMPA) on ... -
Evaluation of the aortic velocity propagation, epicardial fat thickness, and carotid intima-media thickness in patients with subclinical hypothyroidism
Aşoglu, Emin; Akbulut, Tayyar; Doğan, Zeki; Aşoglu, Ramazan (IMR Press, 2021)Subclinical hypothyroidism (SH) is associated with hemodynamic and metabolic abnormalities that cause endothelial dysfunction and atherosclerotic cardiovascular diseases. Aortic velocity propagation (AVP), epicardial fat ... -
Evaluation of the relationship between monocyte to high-density lipoprotein cholesterol ratio and thrombus burden in patients with deep vein thrombosis
Doğan, Zeki; Bektaşoğlu, Gökhan; Dümür, Şeyma; Uzun, Hafize; Erden, İsmail; Yurtdaş, Mustafa (Revista da Associacao Medica Brasileira, 2023)Bu çalışmanın amacı, derin ven trombozlu hastalarda monosit sayısı ve yüksek yoğunluklu lipoprotein kolesterol düzeylerini ve oranlarını (monosit/yüksek yoğunluklu lipoprotein oranı) değerlendirmek ve tanı anında bu oranın ... -
Impact of Promising Biomarkers on Severity and Outcome of Acute Pulmonary Embolism
Sagcan, Gulseren; Doğan, Zeki; Uzun, Hafize; Cuhadaroglu, Cağlar; Okumuş, Gülfer; Arseven, Orhan (Dove Medical Press Ltd, 2023)Background: Acute pulmonary embolism (APE) is a common clinical condition. Its severity ranges from asymptomatic radiological findings to fatal obstructive shock. The potential circulating biomarkers have been studied to ... -
Leadless pacemaker implantation following tricuspid interventions: multicenter collaboration of feasibility and safety
Gül, Enes Elvin; Baudinaud, Pierre; Waldmann, Victor; Sabbag, Avi; Jubeh, Yousef; Clementy, Nicholas; Ollitraut, Pierre; Conti, Sergio; Carabelli, Adrian; Doğan, Zeki (SPRINGER, 2024)BackgroundPermanent pacing is often required following valve intervention (either surgical or percutaneous); however, tricuspid interventions pose specific challenges to conventional pacing. Therefore, leadless pacemaker ... -
Leadless pacemaker implantation following tricuspid interventions: multicenter collaboration of feasibility and safety (Apr, 10.1007/s10840-024-01796-w, 2024)
Gül, Enes Elvin; Baudinaud, Pierre; Waldmann, Victor; Sabbag, Avi; Jubeh, Yousef; Clementy, Nicholas; Bisson, Arnaud; Ollitrault, Pierre; Conti, Sergio; Carabelli, Adrian; Doğan, Zeki (SPRINGER, 2025)Correction -
Liraglutide Enhances Cell Viability and Reduces Oxidative Stress in Hyperglycemic H9c2 Cardiomyocytes
Durmuş, Sinem; Doğan, Zeki; Ergün, Dilek Düzgün; Özdemir, Mahmut; Şahin, Hakan; Şentürk, Gözde Erkanlı; Gelişgen, Remise; Uzun, Hafize (MDPI, 2025)Background and Objectives: Cardiovascular disease remains a leading cause of mortality in Diabetes mellitus (DM), where chronic hyperglycemia induces oxidative stress, mitochondrial dysfunction, and hypoxia in cardiomyocytes. ... -
Lymphocyte to monocyte ratio may predict increased carotid intima-media thickness in patients with subclinical hypothyroidism
Yurtdaş, Mustafa; Aşoglu, Ramazan; Özaydın, Adnan; Doğan, Zeki (IOS PRESS, 2021)AMAÇ: İnflamasyonun ateroskleroz patogenezinde önemli bir rolü vardır. Lenfosit-monosit oranı (LMR) inflamasyonun bir göstergesi olarak kabul edilmektedir. AMAÇ: Amacımız, subklinik hipotiroidizmde (SubHT) karotis intima-media ... -
Percutaneous Coronary Intervention-Related Iatrogenic Fistula in Acute Coronary Syndrome
Yurtdaş, Mustafa; Doğan, Zeki (SPRINGERNATURE, 2024)Iatrogenic coronary artery fistula (CAF) can occur following acute myocardial infarction, percutaneous coronary intervention (PCI) procedures, and heart surgery. Iatrogenic CAF linked to PCI has a low incidence rate. Early ... -
Prasugrel-related hepatotoxicity
Doğan, Zeki; Yurtdaş, Mustafa; Bektaşoğlu, Gökhan (Europe PMC, 2022)Prasugrel, daha güçlü ve daha hızlı antitrombotik aktivasyonu nedeniyle, akut koroner sendrom sırasında perkütan koroner girişim uygulanan hastalarda tekrarlayan koroner tromboz riskini azaltmak için genellikle Klopidogrel'e ... -
Ranolazine exhibits anti-inflammatory and antioxidant activities in H9c2 cardiomyocytes
Doğan, Zeki; Durmus, S.; Ergun, D. D.; Gelişgen, Remise; Uzun, Hafize (Verduci Publisher, 2023)OBJECTIVE: The aim of this study was to evaluate the effectiveness of ranola-zine on hypoxia-inducible factor-1 alpha (HIF-1 alpha) and oxidative stress in H9c2 cardiomyocyte cells.MATERIALS AND METHODS: We have as-sessed ...
