Browsing by Author "Biltekin, Burcu"
Now showing items 1-4 of 4
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Antitumor activity of irinotecan with ellagic acid in C6 glioma cells
Çetin, Abdurrahman; Biltekin, Burcu; Özevren, Hüseyin (Revista da Associação Médica Brasileira, 2022)OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, ... -
Combining Ellagic Acid with Temozolomide Mediates the Cadherin Switch and Angiogenesis in a Glioblastoma Model
Cetin, Abdurrahman; Biltekin, Burcu (Elsevier Science Inc, 2019)OBJECTIVE: We aimed to evaluate the combined effect of ellagic acid (EA) and temozolomide (TEM) on the cadherin switch and angiogenesis in the C6 glioma cell line. METHODS: A total of 100 mu M EA and 100 mu M TEM were ... -
Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects
Ercan, Gülçin; Altınel, Yüksel; Karagülle, Onur Olgaç; Yigitbaş, Hakan; Hacım, Nadir Adnan; Meriç, Serhat; Biltekin, Burcu (Acta Cırúrgıca Brasıleıra, 2021)Purpose: To investigate the efficacy of cordycepin, an adenosine analogue, on prevention of esophageal damage and stricture formation due to esophageal caustic burns in rat model comparing with prednisolone. Methods: Caustic ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an In Vitro Glioblastoma Model
Cetin, Abdurrahman; Biltekin, Burcu; Degirmencioglu, Sevgin (Elsevier Science Inc, 2019)BACKGROUND: The anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. The combined effect of EA with bevacizumab (BEV), a common drug ...