Browsing by ORCID "https://orcid.org/0000-0002-1347-8498"
Now showing items 1-13 of 13
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The Associations between Asprosine, Clusterin, Zinc Alpha-2-Glycoprotein, Nuclear Factor Kappa B, and Peroxisome Proliferator-Activated Receptor Gamma in the Development of Complications in Type 2 Diabetes Mellitus
Şenyiğit, Abdulhalim; Durmuş, Sinem; Tabak, Ömür; Oruç, Aykut; Uzun, Hafize; Ekinci, İskender (MDPI, 2024)Objectives: The aim of this study was to investigate the circulating levels of asprosin, clusterin, zinc-alpha-2-glycoprotein (ZAG), nuclear factor-kappa B (NF-kappa B), and peroxisome proliferator-activated receptor-gamma ... -
CLINICAL SIGNIFICANCE OF SERUM SYNAPTOPHYSIN-LIKE 1 PROTEIN LEVELS IN BREAST CANCER
Kösem, Yağmur Özge Turaç; Uzun, Hafize; Velidedeoğlu, Mehmet; Kocael, Pınar; Dümür, Şeyma; Şimşek, Osman (SOC MEDICAL BIOCHEMISTS SERBIA, 2024)Background: Mammography, used for breast cancer (BC) screening, has limitations such as decreased sensitivity in dense breasts. Currently used tumor markers are insufficient in diagnosing breast cancer. In this study, we ... -
Effects of Bosentan on Hypoxia, Inflammation and Oxidative Stress in Experimental Blunt Thoracic Trauma Model
Uzun, Nedim; Durmuş, Sinem; Gerçel, Gonca; Aksu, Burhan; Mısırlıoğlu, Naile Fevziye; Uzun, Hafize (MDPI, 2024)Background and Objectives: In this study, we aimed to investigate the effects of bosentan, an endothelin receptor antagonist, on endothelin-1 (ET-1), hypoxia-inducible factor-1 (HIF-1), nuclear factor-kappa B (NF-kappa B), ... -
The Epidemiology of Deficiency of Vitamin B12 in Preschool Children in Turkey
Elgörmüş, Yusuf; Okuyan, Ömer; Dümür, Şeyma; Sayılı, Uğurcan; Uzun, Hafize (MDPI, 2023)Background: Vitamin B12 is a water-soluble vitamin with important cellular functions; it is an essential vitamin. The aim of this study is to determine the B12 levels of children in the period from the 6th month when ... -
Evaluation of Glucose 6-Phosphate Dehydrogenase, Pyruvate Kinase, and New Generation Inflammation Biomarkers in Prolonged Neonatal Jaundice
Okuyan, Ömer; Dümür, Şeyma; Elgörmüş, Neval; Uzun, Hafize (MDPI, 2024)Background and Objectives: To evaluate the clinical findings of glucose 6-phosphate dehydrogenase (G6PD) and pyruvate kinase (PK) deficiency in prolonged jaundice and to determine whether the systemic immune inflammation ... -
miRNA-129-3P Expression in Synovial Fluid of Patients with Osteoarthritis
Polat, Sıla Hidayet Bozdoğan; Polat, Abdulkadir; Uzun, Hafize; Şahin, Gülderen; Darıyerli, Nuran (GALENOS PUBL HOUSE, 2022)Objective: The aim of this study was to investigate the miRNA-129-3p expressions in the synovial fluid of patients with a primary knee osteoarthritis (OA), and thereby contribution to the elucidating underlying molecular ... -
New Generation of Systemic Inflammatory Markers for Respiratory Syncytial Virus Infection in Children
Okuyan, Ömer; Elgörmüş, Yusuf; Dümür, Şeyma; Sayılı, Uğurcan; Uzun, Hafize (MDPI, 2023)Aim: This study evaluated the relationship between the systemic immune-inflammatory index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) with clinical findings of respiratory syncytial ... -
Oxidative Stress and Asprosin Levels in Type 2 Diabetic Patients with Good and Poor Glycemic Control
Şenyiğit, Abdulhalim; Durmuş, Sinem; Gelişgen, Remise; Uzun, Hafize (MDPI, 2024)Objectives: HbA1c is the most widely used test as an indicator of glucoregulation in patients with type 2 diabetes mellitus (T2DM). Asprosin and oxidative stress levels can be reduced with good glycemic control (GC) and ... -
The Relationship between Neutrophil-Lymphocyte Ratios with Nutritional Status, Risk of Nutritional Indices, Prognostic Nutritional Indices and Morbidity in Patients with Ischemic Stroke
Mısırlıoğlu, Naile Fevziye; Uzun, Nedim; Özen, Gülenay Defne; Çalık, Mustafa; Altınbilek, Ertuğrul; Sutaşır, Necmettin; Sayılı, Sena Baykara; Uzun, Hafize (MDPI, 2024)Background: In recent years, whole blood parameters and derivatives have been used as prognostic criteria in the course of various diseases. The aim of this study was to evaluate the relationship between parameters such ... -
The Relationship between Vitamin D, Inflammatory Markers, and Insulin Resistance in Children
Okuyan, Ömer; Dümür, Şeyma; Elgörmüş, Neval; Uzun, Hafize (MDPI, 2024)Objective: In this study, we investigated 25-hydroxyvitamin D (25(OH)D, vitamin D), inflammatory hematologic ratios such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation ... -
Role of Reelin and Zinc in the Pathogenesis of D-Glutamic Acid-Induced PAH
Oruç, Kadriye Yağmur; Oruç, Aykut; Altan, Mehmet; Sönmez, Osman Fuat; Yanar, Karolin; Kepil, Nuray; Mengi, Murat; Çakatay, Ufuk; Uzun, Hafize; Şimşek, Gönül (WILEY, 2023)Supplement:730 Special Issue:SI Meeting Abstract:PC-075 -
Serum Otoconin-90 and Otolin-1 Concentrations in Benign Paroxysmal Positional Vertigo
Aygün, Demet; Elgörmüş, Mehmet Nuri; Alpaslan, Mehmet Serkan; Uzun, Hafize; Dümür, Şeyma (MDPI, 2024)Objective: The aim was to evaluate the value of otolith-associated protein otoconin-90 (OC90) and otolin-1 in the pathogenesis research and clinical treatment of benign paroxysmal positional vertigo (BPPV). Material and ... -
Significance of Plasma Irisin, Adiponectin, and Retinol Binding Protein-4 Levels as Biomarkers for Obstructive Sleep Apnea Syndrome Severity
Fazlıoğlu, Nevin; Uysal, Pelin; Durmuş, Sinem; Yurt, Sibel; Gelişgen, Remise; Uzun, Hafize (MDPI, 2023)Objective: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder that is caused by the reduction or cessation of airflow in the upper airway. Irisin, retinol-binding protein-4 (RBP-4), and adiponectin are the ...