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The Role of Glycogen Synthase Kinase-3β in the Zinc-Mediated Neuroprotective Effect of Metformin in Rats with Glutamate Neurotoxicity
Oruc, Aykut; Oruc, Kadriye Yagmur; Yanar, Karolin; Mengi, Murat; Caglar, Aysel; Kurt, Bahar Öztürk; Altan, Mehmet; Sönmez, Osman Fuat; Cakatay, Ufuk; Uzun, Hafize; Simsek, Gönül (Wiley, 2023)Metformin has been suggested to have protective effects on the central nervous system, but the mechanism is unknown. The similarity between the effects of metformin and the inhibition of glycogen synthase kinase (GSK)-3β ... -
The role of laparoscopic sleeve gastrectomy on inflammatory parameters n morbidly obese patients
Ergun, S.; Ergun, D. D.; Akıncı, O.; Taşkın, Halit Eren; Simsek, Gönül; Taşkın, M.; Uzun, Hafize (Elsevier Masson, Corp Off, 2022)Background: Obesity is an excessive increase in body fat mass and triggers chronic inflammation which causes increased fat accumulation in the visceral fat tissue. The aim of this study was to analyze serum zinc (Zn), ...