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Modafinil Improves Autism-like Behavior in Rats by Reducing Neuroinflammation
Bağcıoğlu, Erman; Solmaz, Volkan; Erbaş, Oytun; Özkul, Bahattin; Çakar, Burak; Uyanıkgil, Yiğit; Söğüt, İbrahim (SPRINGER, 2023)To evaluate the ameliorating effect of Modafinil on neuroinflammation, behavioral, and histopathological alterations in rats induced by propionic acid (PPA). Thirty male Wistar rats were used in the study, divided into 3 ... -
Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats
Erdoğan, Mümin Alper; Turk, Miray; Doganay, Gizem Dinler; Sever, İbrahim Halil; Özkul, Bahattin; Söğüt, İbrahim; Eroğlu, Ebru; Uyanikgil, Yigit; Erbaş, Oytun (Springer, 2023)Recent research on placental, embryo, and brain organoids suggests that the COVID-19 virus may potentially affect embryonic organs, including the brain. Given the established link between SARS-CoV-2 spike protein and ... -
Short term protective effect of digitoxin in sepsis-induced acute lung injury
Bora, Ejder Saylav; Erdoğan, Mümin Alper; Özkul, Bahattin; Sever, İbrahim Halil; Söğüt, İbrahim; Hürdağ, Canan; Erbaş, Oytun (Tech Science Press, 2022)Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light its effect ...
