Yazar "Gelişgen, Remise" için listeleme
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Can circulating oxidative stress-related biomarkers be used as an early prognostic marker for COVID-19?
Uysal, Pelin; Yüksel, Arzu; Durmuş, Sinem; Cuhadaroglu, Cağlar; Gelişgen, Remise; Uzun, Hafize (Frontiers Media Sa, 2023)Arka Plan Oksidatif stres birçok hastalığın patogenezinde önemli bir rol oynar. Bu çalışma, yeni COVİD-19 hastalarında nükleer faktör kappa B (NF-kappa B) ile oksidatif stres arasındaki ilişkiyi ve hastalığın ciddiyetini ... -
The effect of nitric oxide, endothelial nitric oxide synthetase, and asymmetric dimethylarginine in hemorrhoidal disease
Gökçe, Aylin Hande; Gökçe, Feridun Suat; Durmuş, Sinem; Hajiyeva, Ramila; Ersöz, Feyzullah; Gelişgen, Remise; Uzun, Hafize (Assoc Medica Brasileira, 2020)AIM: The aim of this study was to examine the roles of nitric oxide (NOx), endothelial nitric oxide synthetase (eNOS), and asymmetric dimethylarginine (ADMA), which is the major endogenous inhibitor of nitric oxide synthases ... -
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy
Doğan, Zeki; Ergun, D. D.; Durmus, S.; Şahin, Hilal; Şentürk, G. E.; Gelişgen, Remise; Senyigit, A.; Uzun, Hafize (Verduci Publisher, 2023)Objective: Oxidative stress and hypoxia play an important role in the pathogenesis of various cardiovascular diseases. We aimed to evaluate the effectiveness of sacubitril/valsartan (S/V) and Empagliflozin (EMPA) on ... -
Maternal serum preptin levels in the pathogenesis and diagnosis of gestational diabetes mellitus
Kıraç Utku, İrem; Demir, Esra; Özkan, Hanişe; Sahtiyancı, Berrak; Uzun, Hafize; Ekinci, İskender; Büyükkaba, Mitat; Durmuş, Sinem; Akarsu, Murat; Gelişgen, Remise; Tabak, Ömür (Society of Medical Biochemists of Serbia, 2023)Background: Gestational diabetes mellitus (GDM) is a metabolic disorder that occurs during pregnancy that increases both maternal and fetal mortality and morbidity. It was investigated whether there is a change in circulating ... -
Prediction of Preterm Delivery Using Serum Ischemia Modified Albumin, Biglycan, and Decorin Levels in Women with Threatened Preterm Labor
Bıyık, İsmail; Soysal, Cenk; İnce, Özlem Ulaş Onur; Durmuş, Sinem; Öztaş, Efser; Keskin, Nadi; Işıklar, Özben Özden; Karaağaç, Oğuz Han; Gelişgen, Remise; Uzun, Hafize (Georg Thieme Verlag KG, 2023)Objective The serum ischemia modified albumin (IMA), biglycan, and decorin levels of pregnant women who were hospitalized for threatened preterm labor were measured.Methods Fifty-one consecutive pregnant women with a single ... -
Ranolazine exhibits anti-inflammatory and antioxidant activities in H9c2 cardiomyocytes
Doğan, Zeki; Durmus, S.; Ergun, D. D.; Gelişgen, Remise; Uzun, Hafize (Verduci Publisher, 2023)OBJECTIVE: The aim of this study was to evaluate the effectiveness of ranola-zine on hypoxia-inducible factor-1 alpha (HIF-1 alpha) and oxidative stress in H9c2 cardiomyocyte cells.MATERIALS AND METHODS: We have as-sessed ... -
Relationship between serum sialic acid levels and prolidase activity with airflow obstruction in patients with COPD
Uysal, Pelin; Teksöz, Duygu; Aksan, Hülya; Durmuş, Sinem; Gelişgen, Remise; Şimşek, Gönül; Uzun, Hafize (Lippincott Williams & Wilkins, 2022)Our aim in this study was to evaluate the prognostic significance of sialic acid (SA) and prolidase activity and to evaluate the association between airflow obstruction severity and these parameters in chronic obstructive ... -
Serum and intestinal tissue zonulin levels in the evaluation of intestinal permeability in rats with acute pancreatitis
Yıldız, Abdullah; Kundaktepe, Berrin Papila; Yüksekdağ, Sema; Durmuş, Sinem; Silav, Zuhal Kuş; Gelişgen, Remise; Ünal, Ethem; Uzun, Hafize (2022)To evaluate the eff ects on malondialdehyde (MDA), superoxide dismutase (SOD), lipid hydroperoxide (LOOH), glutathione (GSH) levels as oxidative stress markers, zonulin levels, and histopathological findings of experimental ... -
Significance of Cyclooxgenase-2 gene polymorphism and related miRNAs in pulmonary arterial hypertension
Durmuş, Sinem; Atahan, Ersan; Avcı Kılıçkıran, Burçak; Önal, Burak; Çakatay, Ufuk; Gelişgen, Remise; Uzun, Hafize (Elsevier, 2022)Background: Pulmonary arterial hypertension (PAH) is a rare disease with a poor prognosis. The suppression of cyclooxygenase-2 (COX-2) expression has been known to impair vascular function in endothelial cells; however, ... -
Significance of Plasma Irisin, Adiponectin, and Retinol Binding Protein-4 Levels as Biomarkers for Obstructive Sleep Apnea Syndrome Severity
Fazlıoğlu, Nevin; Uysal, Pelin; Durmuş, Sinem; Yurt, Sibel; Gelişgen, Remise; Uzun, Hafize (MDPI, 2023)Objective: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder that is caused by the reduction or cessation of airflow in the upper airway. Irisin, retinol-binding protein-4 (RBP-4), and adiponectin are the ...
