Dahili Tıp Bilimleri Bölümü Koleksiyonu
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Assessment of subtle cardiac dysfunction induced by premature ventricular contraction using two-dimensional strain echocardiography and the effects of successful ablation
(Elsevier España S.L.U., 2024)Introduction and objectives: We aimed to assess the effects of successful ablation on impaired left ventricular global longitudinal strain (LV-GLS) in patients with frequent premature ventricular contractions (PVCs). We ... -
Alterations in expression of phosphatase and tensin homologous (PTEN) gene analyzed in the bronchial lavage samples of non-small cell lung cancer patients
(Bayrakol Medical Publishing, 2024)Aim: In this study, we aimed to analyze the expression of the Phosphatase and Tensin Homologous gene (PTEN) by interphase-fluorescence in situ-hybridization (iFISH), and localization and immunoreactivity of PTEN by ... -
Evaluation of Clinical and Immunological Alterations Associated with ICF Syndrome
(Springer/Plenum Publishers, 2024)Purpose: Immunodeficiency with centromeric instability and facial anomalies (ICF) syndrome is a rare autosomal recessive combined immunodeficiency. The detailed immune responses are not explored widely. We investigated ... -
Assessment of sexual dysfunction, the quality of life and difficulties in broaching sexual issues in patients with chronic low back pain by using cluster analysis
(MRE Press, 2024)The aim of this study is to investigate the physical and psychosocial problems and the clinical and sociodemographic factors affecting sexual life in patients with nonspecific chronic low back pain (CLBP), thus drawing ... -
Association Between Serum Irisin Levels and ST-Segment Elevation Myocardial Infarction
(Dove Medical Press Ltd, 2023)Background: An acute ST-elevation myocardial infarction (STEMI) is a serious cardiovascular condition with a high risk of morbidity and mortality. Irisin is adipomyokine that is associated with various health conditions. ... -
Brugada phenocopy associated with multiple psychotic drugs
(Churchill Livingstone is an academic publisher, 2023)Brugada phenocopy (BrP) is a clinical condition characterized by transient ECG changes of Brugada syndrome (BrS), which can be due to various clinical conditions. We describe a case report of BrP due to psychotic drugs. -
Ranolazine exhibits anti-inflammatory and antioxidant activities in H9c2 cardiomyocytes
(Verduci Publisher, 2023)OBJECTIVE: The aim of this study was to evaluate the effectiveness of ranola-zine on hypoxia-inducible factor-1 alpha (HIF-1 alpha) and oxidative stress in H9c2 cardiomyocyte cells.MATERIALS AND METHODS: We have as-sessed ... -
Impact of Promising Biomarkers on Severity and Outcome of Acute Pulmonary Embolism
(Dove Medical Press Ltd, 2023)Background: Acute pulmonary embolism (APE) is a common clinical condition. Its severity ranges from asymptomatic radiological findings to fatal obstructive shock. The potential circulating biomarkers have been studied to ... -
Effects of Cornus mas L. on anthropometric and biochemical parameters among metabolic associated fatty liver disease patients: Randomized clinical trial
(Elsevier Ireland Ltd, 2023)Ethnopharmacological relevance: Cornus mas L. (Cornelian cherry, CM) fruits have been utilized for decades in numerous European and Asian countries as traditional cuisine and folk medicine. CM has antioxidant, anti-diabetic, ... -
The effect of smartphone addiction on vessel wall thickness, which is a predictor of atherosclerosis
(Cambridge University Press, 2023)Aim:The increasing global popularity of smartphone usage has increased concerns about the negative effects of smartphone addiction, such as lack of sleep, sedentary life, bad eating habits, anxiety, stress, and depression, ... -
Evaluation of cognitive deficits in patients infected with COVID-19
(Verduci Publisher, 2022)OBJECTIVE: COVID-19 infection can cause impairments in many cognitive areas. The aim of the present study was to evaluate the cognitive functions of patients who had been infected with COVID-19. PATIENTS AND METHODS: ... -
A Case of CADASIL with NOTCH3 Gene Mutation Presenting with Focal Epileptic Seizure: A Case of CADASIL Presenting with Focal Epileptic Seizure
(Galenos Publishing House, 2023)CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary disease of cerebral microvessels with autosomal dominant inheritance due to the NOTCH3 gene mutation. ... -
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy
(Verduci Publisher, 2023)Objective: Oxidative stress and hypoxia play an important role in the pathogenesis of various cardiovascular diseases. We aimed to evaluate the effectiveness of sacubitril/valsartan (S/V) and Empagliflozin (EMPA) on ... -
Frequency of frontotemporal dementia-related gene variants in Turkey
(Elsevier Science İnc, 2021)Frontotemporal demansın (FTD) klinik heterojenliği gibi genetik temeli de çeşitlidir ve hastalık patogenezinde çok sayıda moleküler yolakların rol oynadığı düşünülmektedir. Bu çalışmada FTD ile ilişkili genler, 175 indeks ... -
Association between the Trp64Arg polymorphism of the ADRB3 gene and overactive bladder
(WILEY HOBOKEN, 2021)Arka Plan Beta(3)-adrenerjik reseptör (ADRB3), insan detrüsör kas fonksiyonunun düzenlenmesinde çok önemlidir. ADRB3 geninin iyi bilinen triptofan64arginin polimorfizmi, reseptörün adrenalin ve noradrenalin dahil olmak ... -
Can circulating oxidative stress-related biomarkers be used as an early prognostic marker for COVID-19?
(Frontiers Media Sa, 2023)Arka Plan Oksidatif stres birçok hastalığın patogenezinde önemli bir rol oynar. Bu çalışma, yeni COVİD-19 hastalarında nükleer faktör kappa B (NF-kappa B) ile oksidatif stres arasındaki ilişkiyi ve hastalığın ciddiyetini ... -
Prasugrel-related hepatotoxicity
(Europe PMC, 2022)Prasugrel, daha güçlü ve daha hızlı antitrombotik aktivasyonu nedeniyle, akut koroner sendrom sırasında perkütan koroner girişim uygulanan hastalarda tekrarlayan koroner tromboz riskini azaltmak için genellikle Klopidogrel'e ... -
Evaluation of Bone Turnover Markers Such as Osteoprotegerin, Sclerostin and Dickkopf-1 in Subclinical Hyperthyroidism
(Springer Nature, 2022)In this study, it was aimed to assess effects of subclinical hyperthyroidism (SH) on bone metabolism using osteoprotegerin (OPG), sclerostin, Dickkopf-1 (DKK1) and biochemical parameters. This cross-sectional prospective ... -
Association between history of polymerase chain reaction-verified covid-19 ınfection and outcomes of subsequent st-elevation myocardial ınfarction
(Sage Publications Inc, 2022)While the acute phase of coronavirus disease 2019 (COVID-19) is associated with worsening cardiac outcomes, it is unclear whether it affects the outcome of patients with ST-segment elevation myocardial infarction (STEMI) ... -
Cardiovascular drugs and analysis of potential risk factors associated with mortality in severe coronavirus disease 2019 patients
(Revista da Associação Médica Brasileira, 2022)OBJECTIVES: Cardiovascular diseases are also considered to increase the risk of death in COVID-19 patients. However, real-world data concerning the risk factors for death in patients with severe COVID-19 still remain ...