Kurum Yazarı "Uzun, Hafize" Tıp Fakültesi İçin Listeleme
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The Role of NF-κB, PPAR-α, and PPAR-γ in Older Adults with Metabolic Syndrome
Demirağ, Filiz; Yavuzer, Serap; Cengiz, Mahir; Yavuzer, Hakan; Kara, Zehra; Ayvacı, Adnan; Avcı, Suna; Yürüyen, Mehmet; Uzun, Hafize; Altıparmak, Mehmet Rıza (Georg Thieme Verlag KG, 2023)The etiopathogenesis of metabolic syndrome (MetS) has not been fully understood yet, and chronic low-grade inflammation is thought to be associated with the development of complications related to MetS. We aimed to investigate ... -
Serum and intestinal tissue zonulin levels in the evaluation of intestinal permeability in rats with acute pancreatitis
Yıldız, Abdullah; Kundaktepe, Berrin Papila; Yüksekdağ, Sema; Durmuş, Sinem; Silav, Zuhal Kuş; Gelişgen, Remise; Ünal, Ethem; Uzun, Hafize (2022)To evaluate the eff ects on malondialdehyde (MDA), superoxide dismutase (SOD), lipid hydroperoxide (LOOH), glutathione (GSH) levels as oxidative stress markers, zonulin levels, and histopathological findings of experimental ... -
Significance of Cyclooxgenase-2 gene polymorphism and related miRNAs in pulmonary arterial hypertension
Durmuş, Sinem; Atahan, Ersan; Avcı Kılıçkıran, Burçak; Önal, Burak; Çakatay, Ufuk; Gelişgen, Remise; Uzun, Hafize (Elsevier, 2022)Background: Pulmonary arterial hypertension (PAH) is a rare disease with a poor prognosis. The suppression of cyclooxygenase-2 (COX-2) expression has been known to impair vascular function in endothelial cells; however, ... -
Thrombospondin 1 and Nuclear Factor Kappa B Signaling Pathways in Non-alcoholic Fatty Liver Disease
Ekinci, İskender; Dumur, Şeyma; Uzun, Hafize; Anataca, Gulden; Yalcinkaya, İsa; Büyükkaba, Mitat (Medıcal Unıv Press, 2022)Amaç: Alkolsüz yağlı karaciğer hastalığında (NAFLD) dolaşımdaki trombospondin-1 (TSP-1) ve nükleer faktör kappa B'yi (NF-κB) bu sinyal yolaklarını karaciğerin inflamatuar ve fibrojenik süreçlerine entegre etmek amacıyla ...