WoS İndeksli Yayınlar KoleksiyonuWoS Indexed Publications Collectionhttps://hdl.handle.net/20.500.12900/62024-03-29T11:30:32Z2024-03-29T11:30:32ZThe Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and PrediabetesFenercioglu, Aysen KutanGonen, Mustafa SaitUzun, HafizeSipahioglu, Nurver TurfanerCan, GunayTas, EbruKara, Zehrahttps://hdl.handle.net/20.500.12900/3252024-03-08T08:48:33Z2023-01-01T00:00:00ZThe Association between Serum 25-Hydroxyvitamin D3 Levels and Pro-Inflammatory Markers in New-Onset Type 2 Diabetes Mellitus and Prediabetes
Fenercioglu, Aysen Kutan; Gonen, Mustafa Sait; Uzun, Hafize; Sipahioglu, Nurver Turfaner; Can, Gunay; Tas, Ebru; Kara, Zehra
In this study, we aimed to reveal the pro-inflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabetes. We recruited 84 prediabetes patients, 94 new-onset T2DM patients and 113 healthy participants. We measured the levels of C-reactive protein (CRP), fibrinogen, ferritin, interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), nuclear factor kappa-B (NF-kappa B) and mitogen-activated protein kinase (MAPK) in the serum of the participants. ANOVA Bonferroni and Kruskal-Wallis Dunn tests were used to compare the inflammation markers and vitamin D levels between the groups. Based on covariance analysis with age, gender and BMI, the Vit D levels of the T2DM group were significantly lower (p < 0.003). Pro-inflammatory markers and CRP were significantly higher in prediabetic and diabetic subjects. In the prediabetes group, IL-1 beta, IL-6, IL-8, TNF-alpha and MAPK were significantly higher in those with Vit D insufficiency and deficiency groups. In the T2DM group, IL-1 beta, IL-6, IL-8, TNF-alpha, NF-kappa B, MAPK and CRP were significantly higher in those with Vit D insufficiency and deficiency. Our study emphasizes the pro-inflammatory effects of Vit D deficiency and insufficiency in new-onset type 2 diabetes mellitus and prediabetes.
2023-01-01T00:00:00ZIndividual factors impacting tourist satisfaction and revisit intention in slow tourism cities: an extended modelBaghirov, FakhriBozbay, ZehraZhang, Yehttps://hdl.handle.net/20.500.12900/3242024-03-05T14:29:52Z2023-01-01T00:00:00ZIndividual factors impacting tourist satisfaction and revisit intention in slow tourism cities: an extended model
Baghirov, Fakhri; Bozbay, Zehra; Zhang, Ye
PurposePostpandemic efforts to rebuild have steered the global economy toward a more sustainable trajectory. It is imperative to acknowledge the pressing need for further enhancements in the sustainable development of the tourism industry. This study aims to examine the influence of personal factors, including environmental concern, cultural interest, travel lifestyle and involvement, on tourist satisfaction and revisit intention, using the theory of planned behavior (TPB) as its framework.Design/methodology/approachThe data was gathered through surveys conducted in three of Turkiye's most famous slow travel destinations: Seferihisar, Gokceada and Akyaka. The analysis was carried out using SPSS and SmartPLS software, with subsequent structural model testing.FindingsThis study presents an extended model that incorporates four individual factors, tourist satisfaction, TPB and revisit intention. All hypotheses have been rigorously tested, and the model accounts for 60.4% of the variance in revisit intention. The findings are comprehensively discussed in this article, supported by relevant theoretical frameworks.Research limitations/implicationsFuture research avenues could delve into the evolution of slow tourism in both developed and developing countries, assess disparities in revisit intentions between slow tourism and mass tourism destinations and investigate the prospects of sustainable tourism development in the postpandemic era.Originality/valueThe authors use the TPB to examine individual factors, tourist satisfaction and revisit intentions, aiming to build an extended model to gain a deeper understanding of the slow tourist decision-making process.
2023-01-01T00:00:00ZPresence of Portomesenteric Venous Gas and Pneumatosis Intestinalis in Nonocclusive Mesenteric Ischemia as a Complication of Transrectal Ultrasound-Guided Prostate BiopsyÖztürk, Nazlı BegümKutlu, Ayça ZeynepIliaz, Raimhttps://hdl.handle.net/20.500.12900/3232024-03-04T12:47:39Z2023-01-01T00:00:00ZPresence of Portomesenteric Venous Gas and Pneumatosis Intestinalis in Nonocclusive Mesenteric Ischemia as a Complication of Transrectal Ultrasound-Guided Prostate Biopsy
Öztürk, Nazlı Begüm; Kutlu, Ayça Zeynep; Iliaz, Raim
A 58-year-old man with a history of mechanical aortic valve replacement, on anticoagulation with warfarin, presented to the
emergency department with hematochezia 1 day after undergoing transrectal ultrasound-guided prostate biopsy. On presentation,
he was found to have hemorrhagic shock. Fluid resuscitation, packed red blood cell transfusion, and empiric antibiotic therapy were
initiated, and the patient was admitted to an intensive care unit. Abdominal-pelvic computed tomography demonstrated portomesenteric venous gas and pneumatosis intestinalis. Colonoscopy showed ischemic ulcers at the ascending colon and stigmata of
recent bleeding at the site of biopsy in the rectum, which was treated endoscopically. The patient was discharged after continued
improvement during hospitalization. On follow-up, the patient continued to be symptom-free, and a repeat colonoscopy demonstrated healing colonic ulcers.
2023-01-01T00:00:00ZThe Vital Role of Diabetes Nurse Educators in Smoking Cessation: A Case Study from TürkiyeÖzcan, ŞeydaÇarkoğlu, AslıNichter, MimiNichter, MarkAydın, Nuranhttps://hdl.handle.net/20.500.12900/3222024-02-29T12:10:27Z2023-01-01T00:00:00ZThe Vital Role of Diabetes Nurse Educators in Smoking Cessation: A Case Study from Türkiye
Özcan, Şeyda; Çarkoğlu, Aslı; Nichter, Mimi; Nichter, Mark; Aydın, Nuran
This paper discusses the development and implementation of a smoking cessation training program for
diabetes nurse educators. People with diabetes who smoke have a significantly higher risk of morbidity
and mortality. Smoking greatly increases diabetes complications. Surveys were conducted to ascertain how
frequently nurses counseled patients to quit and their interest in cessation training. Observations of nursepatient interactions and interviews with diabetes nurses facilitated the development of a culturally sensitive cessation training program. Survey results revealed that diabetes nurse educators recognized the need
for training in smoking cessation, as many patients with diabetes do not consider smoking to be harmful for their health. A two-day workshop was developed for nurses on the specific harms of smoking for
diabetes patients, including hands-on training in cessation counseling and motivational interviewing. Two
months after training, nurses reported that the skills they acquired gave them confidence to counsel patients
but identified four challenges to conducting cessation in their clinical settings. Diabetes nurse educators
can play a pivotal role in delivering cessation. Training and overcoming challenges to implementation are
urgently needed in the time of coronavirus disease 2019 given the dual risks of diabetes and smoking for
severe complications.
2023-01-01T00:00:00Z