Yazar "Erbaş, Oytun" için listeleme
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Atorvastatin Improves the Propionic Acid- Induced Autism in Rats: The Roles of Sphingosine-1-Phosphate and Anti-inflammatory Action
Durankuş, Ferit; Budak, Korkut; Albayrak, Yakup; Sever, İbrahim Halil; Özkul, Bahattin; Uyanıkgil, Yiğit; Albayrak, Neslihan; Erbaş, Oytun (Cureus Inc, 2023)Amaç Bu çalışmanın amacı, atorvastatinin propiyonik asit kaynaklı otizm modelinde sfingozin-1-fosfat ve antiinflamatuar etkilerini artırarak görüntüleme ve beyin dokusu incelemeleri ile faydalarını araştırmaktır. Malzemeler ... -
Demonstration of ameliorating effect of vardenafil through its anti-inflammatory and neuroprotective properties in autism spectrum disorder induced by propionic acid on rat model
Özkul, Bahattin; Urfalı, Furkan Ertürk; Sever, İbrahim Halil; Bozkurt, Mehmet Fatih; Sogut, Ibrahim; Elgörmüş, Çağrı Serdar; Erbaş, Oytun (Taylor & Francis Ltd, 2022)Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology. In this study, we aimed to determine the ameliorating effects of vardenafil in the ASD rat model induced by propionic acid ... -
Medroxyprogesterone acetate improves propionic acid-induced autism rat model and magnetic resonance spectroscopic correlation
Bozkurt, Mehmet Fatih; Bhayal, Muhammad Nasir; Sever, İbrahim Halil; Özkul, Bahattin; Erbaş, Oytun (Bangladesh Pharmacological Society, 2022)The protective effect of medroxyprogesterone acetate on propionic acid induced autism in rats was evaluated. For this purpose, 30 rats were divided into three groups. The significant difference in the levels of IL-17 ... -
Neuroprotective effect of polyethylene Glycol (PEG-3350) on radiation-induced brain injury via membrane stabilization
Sever, I. H.; Özkul, Bahattin; Atasoy, Özüm; Cini, Nilsu; Bozkurt, Mehmet Fatih; Erdogan, M. A.; Yaprak, G; Erbaş, Oytun (IJRR - International Journal of Radiation Research, 2023)Background: This research aims to evaluate whether polyethylene glycol (PEG), which can immediately repair neuronal membranes, will have a protective effect against radiation-induced brain injury (RIBI). Materials and ... -
Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats
Erdoğan, Mümin Alper; Turk, Miray; Doganay, Gizem Dinler; Sever, İbrahim Halil; Özkul, Bahattin; Söğüt, İbrahim; Eroğlu, Ebru; Uyanikgil, Yigit; Erbaş, Oytun (Springer, 2023)Recent research on placental, embryo, and brain organoids suggests that the COVID-19 virus may potentially affect embryonic organs, including the brain. Given the established link between SARS-CoV-2 spike protein and ... -
Protective Effects of Ibudilast Against Cisplatin-Induced Hepatotoxicity and Nephrotoxicity Mediated by Prostacyclin Enhancement
Özkul, Özlem; Özkul, Bahattin; Erdoğan, Mümin Alper; Erbaş, Oytun (Asian Network for Scientific Information (ANSInet), 2023)Background and Objective: Cisplatin, a prevalent chemotherapy drug, presents hepatotoxic and nephrotoxic side effects, this study explores ibudilast's potential protective effects against such damage via prostacyclin ... -
Short term protective effect of digitoxin in sepsis-induced acute lung injury
Bora, Ejder Saylav; Erdoğan, Mümin Alper; Özkul, Bahattin; Sever, İbrahim Halil; Söğüt, İbrahim; Hürdağ, Canan; Erbaş, Oytun (Tech Science Press, 2022)Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light its effect ...